(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)


Fig. 8. Localisation mechanism of pEg2. The N-terminal domain (red) localises the kinase to the centrosomes (grey) through an interaction with a hypothetical protein (blue) that binds to microtubules (black), the localisation being microtubule-dependent. Then the kinase binds to its substrates (yellow), which stabilises the localisation so that it becomes microtubule-independent.