JCS -- Barg et al. 114 (11): 2145 Figure IG3

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)

Fig. 3. ClC-3 channels localize to the B-cell granule membrane. (A) Distribution of anti-hClC-3c binding, insulin immunoreactivity and overlay of anti-hClC-3c and insulin immunoreactivity visualized by confocal immunocytochemistry. Bar, 2 µm. (B) Immunogold detection of ClC-3 localization to insulin-containing secretory granules (SG) visualized by electron microscopy. The 12 nm gold particles appear as small black dots (arrow). Bar, 100 nm. Ly, lysosome.