Fig. 2. The structural domains of the ferritin-H chain plus the series of deletion constructs of myc-tagged ferritin chain. The top shows a diagram of the structural domains (five helices and the loop region) of the wild-type ferritin-H (WT), based on similarities to human ferritin-H (Harrison and Arosio, 1996b). Along the left side are the names of the constructs and their ability to undergo supramolecular assembly (+ or -). Along the right side are their subcellular localizations when transfected into day-14 corneal epithelial cells (CE) and corneal fibroblasts (CF). ‘N’ and ‘C’ indicate their nuclear and cytoplasmic localizations.