Fig. 8. Expression of FAP-1 in pancreatic adenocarcinoma tissue revealed by immunohistochemistry using the C-20 antibody. Note the positive staining in the cytoplasm of pancreatic duct tumor cells of a stroma-rich tumor (a). Immunostaining is absent from an adjacent tissue section where the C-20 antibody had been preincubated with the respective blocking peptide (b), from the stromal compartment of tumor tissue and from pancreatic duct epithelium of a healthy individual (e). Two further tumor tissue specimens with positive staining are illustrated (c,d) of which one displayed a particularly strong immunoreactivity (c). Counterstained with hemalum. Magnification 135x (a,b,d,e); 270x (c).