
Fig. 4. Restoration of the differentiation potential of cells expressing AhR sense
mRNA by treatment with PPAR
2 ligand. Cells expressing AhR sense mRNA
(S) and cells expressing vector mRNA (V) were treated with differentiation
cocktail (IBMX, DEX and insulin; MDI), 10 µM ciglitazone or a combination
of both. Ciglitazone remained in the medium after DEX and IBMX were removed.
On day 6, cells were fixed and stained with oil red O. Similar results were
obtained with independent clones.