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Fig. 2. Amino acid comparison between Wat1 and homologues from other eukaryotes. Amino acid sequence comparison of Wat1 and homologues from human, rat, fly, budding yeast and plant. Identical amino acid residues are emphasised by blue boxes, and, in particular, invariant amino acid residues that are conserved in all the organisms are shown by dark-blue boxes. WD repeats are underlined.