Fig. 4. Inhibitory effect of BB94, TIMP-2 and MT1-MMP antisense oligonucleotides on MCF10A cell migration. 72 hours after the removal of the ring, BB-94 (at 5x10^-6M) and TIMP-2 (1 µg/ml) were added for 1 hour before the quantification of migration speed of cells at the periphery of the outgrowth. MT1-MMP oligonucleotides antisense (+) or scrambled control oligonucleotides (-) were added to the medium immediately after the ring removal for 144 hours before the quantification of the cell migration speed at the periphery of the outgrowth. ^*P<0.05.