Fig. 8. Binding of Fn and 42 kDa Fn fragment to the surfaces of WI-38 fibroblasts is stimulated by TGFß. (A) Binding of [¹²⁵I]42 kDa fragment to untreated or TGFß-treated cells in suspension. (B) Binding of [¹²⁵I]Fn to untreated or TGFß-treated cells in suspension. Nonspecific binding in the presence of excess unlabeled 42 kDa fragment or Fn was subtracted. Where indicated, cells were incubated with 20 µg/ml anti-tTG antibody. The results are representative of three independent experiments (mean±s.e.m.).