JCS -- Dugina et al. 114 (18): 3285 Figure IG3

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Fig. 3. Codistribution and 3D-structure (shadow projections) of vinculin and ${alpha}$ 5ß1 integrin in FAs of control and TGFß-treated fibroblasts. (A) Immature (arrow) and mature (arrowhead) FAs of a control fibroblast (view from ventral side): ${alpha}$ 5ß1 integrin (red) is adjacent to vinculin (green) or colocalised with vinculin (yellow). (B,C) FAs after 5 days of TGFß treatment. (B) Vinculin staining is hidden by ${alpha}$ 5ß1 integrin staining (basal side of the cell). (C) Vinculin and ${alpha}$ 5ß1 integrin co-staining (yellow) in FAs appears after removing the first basal optical sections. The terminal portions of FAs appear surrounded by ${alpha}$ 5ß1 integrin. Bar, 10 µm.