Fig. 1. Interphase nuclear morphology. (a) Nuclei vary in diameter from 4 µm in early interphase up to 9 µm at prophase, (b) chromatin is generally dispersed and (c) there are membrane protrusions (dark blue arrows) and numerous NPCs (d,e), which have a morphology that is similar to other higher eukaryotes such as Xenopus (g), containing a cytoplasmic ring (yellow arrows), cytoplasmic particles (light blue arrows), internal filaments (red arrows) and a central structure (pink arrows). (h) Cross sections of interphase NPCs showing typical NE profiles.