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Fig. 2. Prophase nuclear morphology. (a) Nuclei are spherical with ~9.5 µm diameter. (b) NPCs appear to be partially dismantled and (c) the central channel is less electron dense in TEM thin sections (arrows). (d-f) FESEM also shows that they are empty in the middle, suggesting that the transporter has been removed leaving the star ring. (g-i) Other intermediates observed in prophase.