JCS -- Obermüller et al. 115 (1): 185 Figure IG5

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Fig. 5. Binding of AP1 and AP2 to peptides representing the cytoplasmic tail of Lamp 1, LAP and LAP ${Delta}$ 7. The peptides were immobilised on the surface of a biosensor and probed for the binding of AP1 or AP2 purified from pig brain. From the sensorgrams, the rate constants for association (k_a), the dissociation (k_d) and the equilibrium (K_D) were calculated. It is notable that only the Lamp 1 peptide was able to bind to both adaptors, whereas LAP and LAP ${Delta}$ 7 peptides were only able to bind to AP2.