Fig. 2. The translocon. Two views of the translocon are shown. Sec61 (shown in red) is a heterotrimer and makes up the core of the translocon. TRAM (shown in green) is tightly associated with the translocon and is required for the translocation of many substrates. Other complexes associated with the translocon are signal peptidase (SP; shown in black) and oligosaccharyl transferase (OST; shown in blue).