Fig. 1. Three modes of cytokinesis in Dictyostelium. A series of time-lapse phase contrast images obtained at 30 second intervals are shown. (A) Wild-type AX2 cells were embedded in low melting temperature agarose and cultured without solid surfaces. In this condition, wild-type cells divide using cytokinesis A. (B) mhcA^- cells were cultured on a plastic dish to allow adhesion to a solid surface. Division of mhcA^- cells is driven by cytokinesis B. (C) Multinucleate mhcA^- cells grown in suspension for 3 days were then placed on a plastic dish. These giant cells divide by cytokinesis C. Bars, 10 µm.