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Fig. 2. (A,B) Quantification of the increase in the number of microtubules extending into anterior lamella regions of B16 melanoma cells in response to increased stress imposed by cell body manipulation (A, 22 cells) and stretching of a flexible growth substrate (B, 19 cells). (C) Quantification of the increase of CLIP-170-associated polymerising microtubule tips in lamella regions of B16 melanoma cells in response to increased stress imposed by cell body manipulation (blue, 15 cells) and stretching of a flexible growth substrate (magenta, four cells).