Fig. 1. Schematic representations of the domains of a subgroup A thrombospondin subunit and the recombinant protein units of TSP-1 and TSP-2. Nomenclature: NTD or N, N-terminal domain; o, oligomerisation sequence; C, procollagen module, P, type 1 (properdin) repeat; E, type 2 (EGF-like) repeat; Ca, type 3 repeat/C-terminal globule; CTD, C-terminal globule; Del, deleted. The smaller protein units are designated by the domains they contain. To avoid lengthy terminology, the largest multidomain units are designated by the portions deleted. In the text, each unit is also designated (1) or (2) to indicate whether the protein unit is derived from TSP-1 or TSP-2, respectively.