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Fig. 2. The absence of functional Fak and Cas leads to similar morphological defects in Yersinia uptake. Representative transmission electron micrographs of Fak+/+ MEFs (A), Fak-/- MEFs (B), HeLa/RK5 (C) or HeLa/Cas-{Delta}YXXP (D) cells infected with YP17/pVector.