Fig. 11. Water content in wt and SPARC-null lenses. Lenses of 1 month-old mice were weighed immediately after dissection. After dehydration at 90°C for 16 hours, the dry weight of each lens was determined. (A,B) SPARC^+/+ and SPARC-null (^-/-) lenses, respectively, prior to dehydration. (C,D) ^+/+ and ^-/- lenses, respectively, after dehydration. The ^+/+ lenses lose 72% of their weight upon drying, whereas ^-/- lenses lose 81% of their weight upon drying. Values are derived from six lenses per group.