Fig. 6. Blocking proteasomal degradation leads to nuclear accumulation of ß-catenin. (A) BCAP cells were treated with MG132 for 4 hours and then fixed and stained as indicated. Bar, 10 µm. (B) Cell extracts from the MG132-treated and control BCAP cells were analyzed by western blotting. vin, vinculin; pß-cat, phosphorylated ß-catenin.