Fig. 2. Deduced polypeptide sequence of human NUANCE. Amino acid residues are numbered on the left. The actin binding domain of NUANCE is highlighted in green; 22 detected dystrophin-like spectrin repeats are in cyan, the transmembrane region is in yellow, Klarsicht-like domain is in black and underlined. Predicted nuclear localization signals are shown in blue and are underlined, leucine zippers are in red and underlined.