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Fig. 1. Ultrastructural localization of nascent rRNA molecules within the nucleolus. Immunogold labelling detection of BrUTP-labelled rRNAs on ultrathin sections of isolated nucleoli from ELT cells pulse-labelled for 1 minute (A) and 10 minutes (B). The main nucleolar components are clearly identified: fibrillar centers (FC), dense fibrillar component (DFC) and granular component (GC). Arrows in (A) point to gold particles. Bar, 0.25 µm.