Fig. 4. Ultrastructural analysis of cell-cell contacts. (a,b) Scanning electron microscope analysis of subconfluent T98G (a) and U373MG cells (b). The arrows indicate thin parallel cellular processes contacting neighbouring T98G cells (a) or lamellipodia-like structures (b). The arrowheads indicate sparse, branched and thin cellular processes making contact with the substratum (b) (Bars, 5 µm). (c-f) Transmission electron microscope analysis of confluent T98G (c,e) and U373MG (d,f) cells, showing perpendicular (c,d) and parallel sections (e,f). The arrows in (e) indicate well defined adherens junctions. (c,d, bars, 1 µm) (e,f, bars, 0.3 µm).