Fig. 6. The effect of APM, a plant-specific microtubule-depolymerizing agent, on telomere clustering. Representative nuclei are displayed as sequential projections of the three-dimensional nucleus, as in Fig. 3a. Control and 25 µM APM-treated anthers were cultured for 14 hours. Telomeres (green) were detected by FISH using a probe to the telomere repeat, and chromatin (red) was stained with DAPI. Bar, 10 µm.