Fig. 1. TWEAK binding to HUVECs is dose-dependent and specific. Mean fluorescence intensity (MFI) versus TWEAK concentration is shown (left), with the dotted line indicating the background MFI with the indirect detection step alone. The traces (right) correspond to (1) background fluorescence with indirect detection step alone, (2) TWEAK binding and (3) inhibition of TWEAK binding by the AB.D3 mAb.