Fig. 2. Effect of dbcAMP, 8-bromo-cAMP or Sp-cAMPs pretreatment on 5-HT-induced GVBD. Oocytes were pretreated using various indicated concentrations of dbcAMP (A), 8-bromo-cAMP (B) or Sp-cAMPs (C) for 15 minutes prior to the addition of 5-HT (5 µM). dbcAMP, dbcAMP alone; 8-Br-cAMP, 8-bromo-cAMP alone; Sp-cAMPs, Sp-cAMPs alone. Mean results (±s.e.m.) of four experiments are shown.