Fig. 1. The scaffold protein IB1/JIP-1 is present in urothelial cells of rat bladder. In situ hybridisation using two non-overlapping cDNA probes specific for IB1/JIP-1 (A,B) demonstrated the presence of IB1/JIP-1 transcripts in the urothelium of rat bladder. These transcripts are translated into immunodetectable protein in non-dilated and dilated bladder respectively (C,D). Smooth muscle cells (smc); Urothelium (u); Lumen (l). Bar represents 15 µm in A and C and 25 µm in B and D.