Fig. 3. Analysis of sex body formation and disappearance in wild type (a-c),
Xisttrun (a'-c') and
Xist1lox (a''-c'') spermatocytes using the sex
body marker
-H2AX. (
-H2AX, green; SYCP3, red; X chromosome,
short arrow; Y chromosome, arrowhead).
-H2AX labels the sex chromosomes
prior to their incorporation into the sex body (a,a',a'') and then
associates with the sex body throughout pachytene (b,b',b''). It
finally disappears as sex bodies are disassembled, at metaphase I
(c,c',c''). Bar, 10 µm.