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Fig. 5. Analysis of macroH2A1.2 localisation in wild type (a,b), Xisttrun (a',b') and Xist1lox (a'',b'') pachytene spermatocytes. (MacroH2A1.2, green; SYCP3, red; X chromosome, short arrow; Y chromosome, arrowhead). MacroH2A1.2 is enriched in the chromatin of the sex chromosomes during early pachytene in all three genotypes. Bar, 10 µm.