Fig. 6. Increased proliferation of the Schwann cell lineage in the mutant sciatic nerves. (A) Merged images of indirect immunofluorescence detection of BrdU (green) and Krox-20 (red) in longitudinal sections of sciatic nerves from control and mutant animals at P97. Krox-20/BrdU double-positive cells are shown in yellow. Counterstaining was performed with Hoechst. (B) Quantitation of BrdU/Krox-20 double-positive cells from control and mutant animals at P37, P97, and P157.