Fig. 5. Synd1 ko mice show delayed re-epithelialization of full-thickness cutaneous wounds. Histology performed on fixed tissues shows that as soon as 5 days (d) after wounding, signs of defective re-epithelialization are detected in the synd1 ko mice compared to wildtype. Low magnification shows wound margins 5 days after wounding, and high magnification shows the poor overall morphology of the synd1 ko tissue compared with wild-type at 5, 7 and 9 days after wounding. Bar, 300 µm in the lower magnification image at day 5, bar, 50 µm in images at days 5 and 7, and bar, 25 µm in the images at day 9.