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Fig. 9. Putative cPLA2-{alpha} nuclear localisation and export signals. (A) Amino-acid sequence of human cPLA2-{alpha}. The potential NLSs are highlighted in blue and green. The potential nuclear export signal is outlined in yellow. (B) 3D structure of cPLA2-{alpha}, showing the positions of the potential NLSs and NES in their respective colours. Also highlighted are the approximate locations of the phosphorylation sites, Ser505 and Ser727.