JCS -- Hinkle et al. 115 (23): 4685 Figure IG1

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Fig. 1. Ran associates with the chromosomes. (A) In meiosis-II-metaphase-arrested Xenopus eggs, double-labeling of Ran by immunofluorescence and chromosomes by Hoechst dye shows colocalization of Ran and chromosomes. (B) Microinjected Rh-Ran is associated with the chromosomes in Xenopus eggs. (C) Microinjected Rh-Ran is associated with chromosomes in mature mouse eggs. The dark circular region in the egg is the oil drop from the injection. Bars, 10 µm.