Fig. 1. Identification of the DOCK180 superfamily of proteins. (C,D) Multiple
sequence alignment of the DHR-1 (C) and DHR-2 (D) domains. DHR-1 and DHR-2
sequences from representative members of the human DOCK180 superfamily were
aligned with ClustalW and the final output was generated by BoxShade. Black
and gray shading indicate identical and similar residues, respectively.
Identical residues are indicated in capital letters and similar residues in
lower-case letters in the consensus sequence.