JCS -- Christensen et al. 115 (3): 599 Figure IG4

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Fig. 4. A time course showing ratiometric measurements of lysosomal pH ( ${circ}$ ) and [Ca²⁺]_lys ([UNK]) following the addition of buffer containing 10 mM NH₄Cl. Lysosomes were labeled with a probe cocktail containing furaDx, FDx and OGDx. Arrow `a' indicates time of addition of NH₄Cl. Arrow `b' indicates time of addition of NH₄Cl-free buffer (RB) causing rapid reacidification and restoration of high [Ca²⁺]_lys. Error bars represent the s.e.m. (n $>=$ 9 cells).