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Fig. 6. Detection of p63RhoGEF mRNA by in situ hybridization in human heart and brain tissue sections. (A) Light microscopy of p63RhoGEF in situ hybridization in human brain. Brightfield (a,e) and darkfield (b) illuminations show the specific hybridization signal observed in body cells localized in the cerebral cortex. Control serial sections were incubated with the sense probe (c,d,f). Bars, 20 µm. (B) Light microscopy of p63RhoGEF in situ hybridization in human heart left ventricle. Brightfield (a,e) and darkfield (b) illuminations show the weak but specific hybridization signal observed in cardiomyocytes. Control sections were incubated with the sense probe (c,d,f). Bar, 10 µm.