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Fig. 2. Other HDAC-containing co-repressor complexes identified by biochemical purification, including the Sin 3-SAP (Sin-associated proteins) complex (Zhang et al., 1997; Zhang et al., 1998c), the NURD (nucleosome remodeling and histone deacetylation) complex (Tong et al., 1998; Xue et al., 1998; Zhang et al., 1998b; Zhang et al., 1999), a NURD-related HDAC-complex (Humphrey et al., 2001) and a CoREST-HDAC complex (Humphrey et al., 2001; You et al., 2001). Dashed outlines indicate the molecule that was used to purify each complex.