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Fig. 7. Decreased expression of MT1-MMP, but not MMP-2, mRNA in Egfr-/- mice. Lung from 18.5 dpc (E18.5) wildtype (a,b) or Egfr-/- (c,d) used to detect MMP-2 (a,c) and MT1-MMP (b,d) mRNA by in situ hybridization. Note the abundant presence of MMP-2 and MT1-MMP mRNA in a,b,c, and absence of MT1-MMP in d. Bar, 100 µm (a-d).