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Fig. 7. The effect of down-regulation of Rab5a on the phagocytic capacity of neutrophils. Neutrophils either treated with Rab5a antisense and then allowed to ingest ({square}) H37Rv or ({blacksquare}) S. aureus, or with Rab5a sense and then phagocytosed (stripes) H37Rv or (grey) S. aureus as described in Materials and Methods. The percentage of the phagocytosed cells with >=1 bacteria was counted by trypan blue exclusion. Data represent mean¶s.e.m. of four experiments.