Fig. 3. Survival of DNA-ligase-I-deficient cells exposed to the following DNA
damaging agents (A) UV; (B) EMS; (C) 3-aminobenamide (3-AB); and (D)
-irradiation. Mean survival±s.e.m. is shown relative to
non-treated controls.
, mouse wild-type (PF20);
, mouse
Lig1 null (PFL13);
, mouse Lig1 null (PFL10);
,
human wild-type (MRC5);
, human LIG1 point mutant (46BR); closed
hexagon, mouse Ercc1 null (PF24).