Fig. 1. Global unrooted phylogeny of syntaxin paralogs. This figure illustrates the basic resolution of syntaxin paralogs into five families of varying support and placement of new syntaxin sequences provided by this study (shown in bold). Support values for critical nodes are shown in the inset table with ProtML RELL values/Quartet Puzzling values/Puzzleboot values. For clarity and because internal relationships of the sub-families are more rigorously tested in later analyses, internal nodes for the clades are simply denoted with an asterisk if the ProtML RELL support is greater than 50%. The dashed line linking the fungal endosomal syntaxins to the metazoan and plants ones denotes that all endosomal syntaxins were monophyletic in consensus trees, but did not appear so in the single best tree. Coloured boxes denote the different syntaxin paralog families, with syntaxin PM homologs in red, endosomal homologs in purple, TLG2/syntaxin 16 homologs in blue, syntaxin 6 in green and syntaxin 5 in yellow.