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Fig. 8. CD spectra of model peptides representing wild-type (A) and P446L mutant importin-ß (B). The CD spectra were recorded in 100% trifluoro-ethanol (TFE, continuous lines), in a mixture of 66% TFE and 33% H2O (dashed lines), and in 33% TFE and 66% H2O (dotted lines).