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Fig. 1. (A) The behavioral responses of wild-type cells to the spatial, temporal and concentration components of the different phases of the natural cAMP wave, derived from results obtained in prior studies (Varnum-Finney et al., 1987a; Varnum-Finney et al., 1987b; Wessels et al., 1992; Wessels et al., 2000b). (B) Protocols used in this study to determine the behavioral defects of S13A mutant cells.