Fig. 2. Localization of CEP110 within the centrosome tube. HeLa centrosomes were stained with the autoimmune serum M4491 (red) and an anti-CEP110 antibody (green). The diagram on the left shows the views of the centrosomes seen in the images on the right. (a,b) The centrosomes before duplication. (c,d) The centrosomes in the process of duplication. (e) The centrosomes after duplication and separation. The arrow denotes the mother centrosomes when the centrosome is still in the process of duplication (c,d) or when duplication and separation are completed (e). The arrowhead denotes the daughter centrosomal bud (c,d) or the fully-formed daughter centrosome (e). Bar, 5 µM.