Fig. 4. Effect of hypoxia on FGF2-induced cell growth. Growth of CMEC and HUVEC in 0.25% serum in the presence (+) or absence (-) of FGF2 (10 ng/ml) was determined after 48 hours of hypoxia (+) or normoxia (-). For each condition, the cells counts are normalized to the baseline number taken as 100%. Note increased growth response to FGF2 for both cell types cultured under hypoxic conditions. ^*P<0.05 hypoxia versus normoxia.