Fig. 8. Chelating extracellular Ca²⁺ inhibited whole-cell currents in swollen erythrocytes. Cells were maintained at a holding potential of -15 mV and stepped to potentials between -100 to +100 mV in 20 mV intervals. (A) Whole-cell currents for an erythrocyte exposed to a hypotonic (0.5x) KCl Ringer solution and inhibition of these currents by adding EGTA (5 mM) to the bath. (B) Corresponding current-voltage (I-V) relationship for control (hypotonic Ringer) and low Ca²⁺ solutions (n=5). Values are means±s.e.m.