Fig. 1. Stable cell lines expressing GFP-SMN show normal nuclear morphology.
Three-dimensional projections of deconvolved serial sections showing cells
from line GFP-SMNE10.3 (green) counterstained with antibodies to Sm proteins
(A-C), coilin (D-F) and SIP1/Gemin2 (G-I). GFP-SMN co-localises in Cajal
bodies with Sm proteins (arrows in C), coilin (arrows in F) and SIP1/Gemin2
(arrows in I). Sm-containing speckles are also visible (arrowheads in C). Bar,
10 µm.