Fig. 5. Time-lapse analysis of interphase cells shows fusion and separation of GFP-SMN Cajal bodies and close interactions between bodies. A-C show 3D projections of serial sections of living cells from line GFP-SMNE10.3 taken from a time series. (A) Fusion of a small body (arrow) with a larger one. (B) Separation of a large body (arrow) into two smaller ones. (C) Close interaction between two bodies (arrow). The frequency of these and other events are shown in panel D.