Fig. 8. A cyclin E mutation fails to suppress skpA-induced centrosome overduplication in the CNS from larvae 3.5 days AED. (A-B) Supernumerary centrosomes in skpA¹; cycE^k05007 mitotic cells. Shown are cycE^k05007 and skpA¹; cycE^k05007 mutant cells with two and six centrosomes, respectively. (C) Quantification of mitotic index and centrosome numbers in different genotypes. Mitotic index and centrosome numbers were calculated as in Fig. 3A and 5G, respectively. Bars, 5 µm.