Fig. 5. (Left) Histogram showing the decrease of uPa expression level in PTHrP-treated cells following incubation with 600 nM hsbp1-asODN or 1 µg geldanamycin/ml. (Right) Ethidium bromide-stained agarose gels of cDNA of preparations from scrambled-asODN-treated (A), hsbp1-asODN-treated (B), control untreated- (C) and geldanamycin-treated 8701-BC cells (D) cultured in the presence of 1 nM PTHrP [67-86]-amide, amplified in multiplex by primers for MMP-1 and ß-actin.