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Fig. 4. Dose dependence of glutamate-induced [Ca2+]c rises. (A) The [Ca2+]c rises in response to different glutamate concentrations in the same cell. (B) The concentration-response curve of the glutamate-induced [Ca2+]c rises. The concentration of the half-maximum [Ca2+]c rise (EC50) is 3.9±1.0 µM. All the solutions contain 1 µM glycine. Each point represents the average of 4-20 cells (mean ± s.e.m.).